Publications

  1. Stachler MD, Bartlett JS. Mosaic vectors comprised of modified AAV1 capsid proteins for efficient vector purification and targeting to vascular endothelial cells. Gene Ther. 2006; 13(11): 926-31.
  2. Arnold GS, Sasser AK, Stachler MD, Bartlett JS. Metabolic biotinylation provides a unique platform for the purification and targeting of multiple AAV vector serotypes. Mol Ther. 2006; 14(1): 97-106.
  3. Stachler MD, Chen I, Ting AY, and Bartlett JS Site specific modifications of AAV vector particles with biophysical probes and targeting ligands using biotin ligase. Mol Ther. 2008; 16(8): 1467-73.
  4. Giardino AA, Ramaiya NH, Shinagare AB, Jagannathan JP, Stachler MD, Raut CP. Case report: Calcifying fibrous tumor presenting as an asymptomatic pelvic mass. Indian J Radiol Imaging. 2011 21(4):306-8.
  5. Baker, K., Rath, T., Flak, M.B., Arthur, J.C., Chen, Z., Glickman, J.N., Zlobec, .I, Karamitopoulou, E., Stachler, M.D., Odze, R.D., Lencer, W.I., Jobin, C., Blumberg, R.S.  Neonatal Fc Receptor Expression in Dendritic Cells Mediates Protective Immunity against Colorectal Cancer. Immunity 2013; 39(6):1095-107.
  6. Kanarek, N., Grivennikov, S., Leshets, M., Lasry, A., Alkalay, I., Horwitz, E., Shaul, Y.D., Stachler, M., Elena Voronov, E., Apte, R.N., Pagano, M., Pikarsky, E., Karin, M., Ghosh, S., and Ben-Neriah, Y.  A critical role for IL-1β in DNA damage-induced mucositis. PNAS 2013; 111(6):702-11.
  7. Hong, Y.S., Kim, J., Fox, C., Ma, Q., Wong, G.S., Pectasides, E., Peng, S., Stachler, M.D., Thorner, A.R., Van Hummelen, P., Bass., A.J. Src mutation induces acquired lapatinib resistance in ERBB2-amplified human gastroesophageal adenocarcinoma models. PLOS One 2014; 9(10): e109440.
  8. Stachler M, Jia Y, Sharaf N, Wade J, Longtine J, Garcia E, Sholl LM. Filter Paper-based Nucleic Acid Storage in High-throughput Solid Tumor Genotyping. AIMM 2015 23(5): 389-96.
  9. Baden, L. R., Liu, J., Li, H., Johnson, J. A., Walsh, S. R., Kleinjan, J. A., Engelso, B. A., Peter, L., Abbink, P., Milner Jr, D. A., Golden, K. L., Viani, K. l., Stachler, M. D., Chen, B. J., Pau, M. G., Weijten, M., Carey, B. R., Miller, C. A., Swann, E. M., Wolff, M., Loblein, H., Seaman, M. S., Dolin, R., Barouch, D. H.  Induction of HIV-1- specific mucosal immune responses following intramuscular recombinant adenovirus serotype 26 HIV-1 vaccination of humans. J Infect Dis. 2015; 211(4):518-28.
  10. Stachler, M.D., Rinehart, E., Lindeman, N., Odze, N., Srivastava, A. "Novel Molecular Insights from Routine Genotyping of Colorectal Carcinomas. Hum Pathol. 2015; 46(4): 507-13.
  11. Stachler, MD.#, Taylor-Weiner, A.#, Peng, S., McKenna, A., Leshchiner, I., Stewart, C., Stojanov, P.,Chauvin, S., Lawrence, M.S., Ferrer-Torres, D., Lin, J., Chang, A.C., Gabriel, S.B., Lander, E.S., Beer, D.G., Carter*, S.L., Getz*, G., Bass*, A.J. Paired Exome Analysis of Barrett’s Esophagus and Adenocarcinoma Reveals Distinct Paths to Cancer. Nature Genetics. 2015 Sep;47(9):1047-55.
  12. Derks S, Nason KS, Liao X, Stachler MD, Liu KX, Liu JB, Sicinska E, Goldberg MS, Freeman GJ, Rodig SJ, Davison JM, Bass AJ.  Epithelial PD-L2 expression marks Barrett’s esophagus and Esophageal Adenocarcinoma.  Cancer Immunol Res. 2015 Oct;3(10):1123-9.
  13. Stachler, M.D., Rinehart, E., Garcia, E., Lindeman, N. PIK3CA Mutations Are Common In Many Tumor Types And Are Often Associated With Other Driver Mutations.  AIMM 2016 May-Jun;24(5):313-9.
  14. Zhou J, Wu Z, Wong G, Pectasides E, Nagaraja A, Stachler M, Zhang H, Chen T, Zhang H, Liu JB, Xu X, Sicinska E, Sanchez-Vega F, Rustgi AK, Diehl JA, Wong KK, Bass AJ.  CDK4/6 or MAPK blockade enhances efficacy of EGFR inhibition in oesophageal squamous cell carcinoma. Nat Commun. 2017 8:13897.
  15. Pectasides E#, Stachler MD#, Derks S#, Liu Y#, Maron S#, Islam M, Alpert L, Kwak H, Kindler H, Polite B, Sharma MR, Allen K, O'Day E, Lomnicki S, Maranto M, Kanteti R, Fitzpatrick C, Weber C, Setia N, Xiao SY, Hart J, Nagy R, Kim KM, Choi MG, Min BH, Nason KS, O'Keefe L, Watanabe M, Baba H, Lanman R, Agoston AT, Oh DJ, Dunford A, Thorner AR, Ducar MD, Wollison BM, Coleman HA, Ji Y, Posner MC, Roggin KK, Turaga K, Chang P, Hogarth K, Siddiqui U, Gelrud A, Ha G, Freeman SS, Rhoades J, Reed S, Gydush G, Rotem D, Davison J, Imamura Y, Adalsteinsson V, Lee J, Bass AJ, Catenacci DV. Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma. Cancer Discov. 2018 8(1):37-48.
  16. Johncilla M, Stachler M, Misdraji J, Lisovsky M, Yozu M, Lindeman N, Lauwers GY, Odze RD, Srivastava A. Mutational landscape of goblet cell carcinoids and adenocarcinoma ex goblet cell carcinoids of the appendix is distinct from typical carcinoids and colorectal adenocarcinomas. Mod Pathol. 2018 31(6):989-996.
  17. Stachler MD#, Camarda ND#, Deitrick C, Kim A, Agoston AT, Odze RD, Hornick JL, Nag A, Thorner AR, Ducar M, Noffsinger A, Lash RH, Redston M, Carter SL*, Davison JM*, Bass AJ*. Detection of Somatic Mutations in Barrett’s Esophagus Prior to Progression to High-grade Dysplasia or Adenocarcinoma. Gastroenterology. 2018 155(1):156-67.
  18. Yu M#, Maden S#, Stachler MD#, Kaz AM, Guo Y, Carter KT, Heinzerling TJ, O’Leary RM, Xu X, Bass A, Chak A, Willis JE, Markowitz SD, Grady WM. Subtypes of Barrett’s esophagus and esophageal Adenocarcinoma based on genome-wide methylation analysis. GUT. 2018  (In Press)
  19. Soong RT , Nayor J, Stachler M, Perencevich M, Jajoo K, Saltzman J, Lindeman NI, Srivastava A. Clinicopathologic and Genetic Characteristics of Interval Colorectal Carcinomas favor origin from missed or incompletely excised precursors. Mod Pathol 2018 (In Press).
  20. Qureshi AP, Stachler MD, Haque O, Odze RD. Biomarkers for Barrett's esophagus - a contemporary review. Expert Rev Mol Diagn. 2018 Nov;18(11):939-946.